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Material Safety Data Sheet
IPA Methanol

ACC# 89493
Section 1 - Chemical Product and Company Identification

MSDS Name: IPA Methanol
Catalog Numbers: A462SS-200
Synonyms: Mixture
Company Identification:
              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
67-63-0 Isopropyl alcohol 99.75 200-661-7
67-56-1 Methyl Alcohol 0.18 200-659-6
91-22-5 Quinoline 0.07 202-051-6

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: Not available. Flash Point: 11.7 deg C.
Warning! Flammable liquid and vapor. May cause eye, skin, and respiratory tract irritation. May cause central nervous system depression. May form explosive peroxides. May cause kidney damage.
Target Organs: Kidneys, central nervous system.


Potential Health Effects
Eye: Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Skin: Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis. May cause allergic skin reaction in some

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Urine acetone test may be helpful in diagnosis.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media: Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Flash Point: 11.7 deg C ( 53.06 deg F)
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: ; Flammability: ; Instability:

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. A vapor suppressing foam may be used to reduce vapors.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Isopropyl alcohol 200 ppm TWA; 400 ppm STEL 400 ppm TWA; 980 mg/m3 TWA 2000 ppm IDLH 400 ppm TWA; 980 mg/m3 TWA
Methyl Alcohol 200 ppm TWA; 250 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute 200 ppm TWA; 260 mg/m3 TWA 6000 ppm IDLH 200 ppm TWA; 260 mg/m3 TWA
Quinoline none listed none listed none listed

OSHA Vacated PELs: Isopropyl alcohol: 400 ppm TWA; 980 mg/m3 TWA Methyl Alcohol: 200 ppm TWA; 260 mg/m3 TWA Quinoline: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:Not available.
Molecular Weight:Not available.

Section 10 - Stability and Reactivity


Chemical Stability: Stable. This material may be sensitive to peroxide formation.
Conditions to Avoid: This material may be sensitive to peroxide formation., incompatible materials, ignition sources.
Incompatibilities with Other Materials: Strong oxidizers, acetaldeyde, chlorine, ethylene oxide, acids and isocyanates, hydrogen + palladium, nitroform, oleum, phosgene, potassium t-butoxide, oxygen, trinitromethane, barium perchlorate, tetrafluoroborate, chromium trioxide, sodium dichromate + sulfuric acid, aluminum, and aluminum triisopropoxide. Methanol is incompatible with acetyl bromide, alkylauminum solutions, beryllium hydride, carbon tetrachloride + metals, chloroform + sodium hydroxide, cyanuric chloride, dichloromethane, diethylzinc, metals, oxidants, phosphorus (III) oxide, and potassium tert-butoxide. Quinoline is incompatible dinitrogen tetraoxide, hydrogen peroxide, linseed oil + thionyl chloride, maleic anhydride + bases. Isopropyl alcohol has also been reported to be susceptible to autoxidation and should therefore be considered peroxidizable.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: May occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 67-63-0: NT8050000      
CAS# 67-56-1: PC1400000      
CAS# 91-22-5: VA9275000
LD50/LC50:
CAS# 67-63-0:
     Draize test, rabbit, eye: 100 mg Severe;
     Draize test, rabbit, eye: 10 mg Moderate;
     Draize test, rabbit, eye: 100 mg/24H Moderate;
     Draize test, rabbit, skin: 500 mg Mild;
     Inhalation, mouse: LC50 = 53000 mg/m3;
     Inhalation, rat: LC50 = 16000 ppm/8H;
     Inhalation, rat: LC50 = 72600 mg/m3;
     Oral, mouse: LD50 = 3600 mg/kg;
     Oral, mouse: LD50 = 3600 mg/kg;
     Oral, rabbit: LD50 = 6410 mg/kg;
     Oral, rat: LD50 = 5045 mg/kg;
     Oral, rat: LD50 = 5000 mg/kg;
     Skin, rabbit: LD50 = 12800
CAS# 67-56-1:
     Draize test, rabbit, eye: 40 mg Moderate;
     Draize test, rabbit, eye: 100 mg/24H Moderate;
     Draize test, rabbit, skin: 20 mg/24H Moderate;
     Inhalation, rabbit: LC50 = 81000 mg/m3/14H;
     Inhalation, rat: LC50 = 64000 ppm/4H;
     Oral, mouse: LD50 = 7300 mg/kg;
     Oral, rabbit: LD50 = 14200 mg/kg;
     Oral, rat: LD50 = 5600 mg/kg;
     Skin, rabbit: LD50 = 15800 mg/kg;
.

CAS# 91-22-5:
     Draize test, rabbit, skin: 100 mg/24H Moderate;
     Oral, rat: LD50 = 331 mg/kg;
     Skin, rabbit: LD50 = 540 uL/kg;
.

Carcinogenicity:
CAS# 67-63-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 67-56-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 91-22-5:


Epidemiology: Early epidemiological studies suggested an association between the strong acid manufacture of isopropyl alcohol and paranasal sinus cancer in workers. The risk of laryngeal cancer may also be increased in these workers. However, it has not been tested adequately in animals to assess its carcinogenicity.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: No data available. Acute aquatic effects: Fathead minnow: LC50 =1000 mg/L/96 Hr. Golden orfe: LC50 = 8970 mg/L/48 Hr. goldfish: LC50 = GT5000 mg/L/24 Hr.
Environmental: This chemical has a low potential to affect aquatic organisms, secondary waste treatment microorganisms, and the germination and growth of some plants. It is readily biodegradable and is not expected to persist in an aquatic environment. It is not likely to bioconcentrate.
Physical: None
Other: None

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 67-56-1: waste number U154 (Ignitable waste).

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: FLAMMABLE LIQUIDS, N.O.S. No information available.
Hazard Class: 3
UN Number: UN1993
Packing Group: II

Section 15 - Regulatory Information

US FEDERAL
TSCA
     CAS# 67-63-0 is listed on the TSCA inventory.
     CAS# 67-56-1 is listed on the TSCA inventory.
     CAS# 91-22-5 is listed on the TSCA inventory.
Health & Safety Reporting List
     CAS# 67-63-0: Effective 12/15/86, Sunset 12/15/96
Chemical Test Rules
     CAS# 67-63-0: 40 CFR 799.2325
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ      CAS# 91-22-5: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 67-63-0: immediate, delayed, fire.
     CAS # 67-56-1: immediate, fire.
     CAS # 91-22-5: immediate.
Section 313
     This material contains Isopropyl alcohol (CAS# 67-63-0, 99.75%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
     Methyl Alcohol is not at a high enough concentration to be reportable under Section 313.
     Quinoline is not at a high enough concentration to be reportable under Section 313.
Clean Air Act:
     CAS# 67-56-1 is listed as a hazardous air pollutant (HAP).
     CAS# 91-22-5 is listed as a hazardous air pollutant (HAP).
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 91-22-5 is listed as a Hazardous Substance under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 67-63-0 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 67-56-1 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
     CAS# 91-22-5 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65
WARNING: This product contains Quinoline, a chemical known to the state of California to cause cancer.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     F
Risk Phrases:
     R 11 Highly flammable.

Safety Phrases:
     S 16 Keep away from sources of ignition - No smoking.
     S 7 Keep container tightly closed.

WGK (Water Danger/Protection)
     CAS# 67-63-0: 1
     CAS# 67-56-1: 1
     CAS# 91-22-5: 2
Canada - DSL/NDSL
     CAS# 67-63-0 is listed on Canada's DSL List.
     CAS# 67-56-1 is listed on Canada's DSL List.
     CAS# 91-22-5 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
     CAS# 67-63-0 is listed on the Canadian Ingredient Disclosure List.
     CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
     CAS# 91-22-5 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 10/16/1997
Revision #6 Date: 10/31/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.